及方华,女,汉族,1987年出生于河北省任丘市,理学博士。现在桂林理工大学化学与生物工程学院从事教学与科研工作
一、教学与工作经历
2016.12-至今 桂林理工大学,化学与生物工程学院,任教;
2011.9-2016.7 华南理工大学,绿色化学研究中心,有机化学专业,
硕士/博士连读,导师:江焕峰,尹标林;
2007.9-2011.7 德州学院,化学工程与工艺专业,学士。
二、所获奖励
首届全国高校教师教学创新大赛校内选拔赛一等奖
桂林理工大学第三届“课程思政”说课比赛理工科组一等奖
桂林理工大学首届“课程思政优秀教案”奖
第七届“化生杯”教师授课比赛一等奖
三、所获荣誉
桂林理工大学“课程思政优秀教师”
2018-2019年度“优秀班主任”
2017-2018年度“优秀班主任”
四、科研工作
主要研究方向:小分子参与的杂环化合物的构建;过渡金属催化的杂环化合物的构建等方法学研究。
主持科研项目:
国家自然科学基金40万,2021年1月-2024年12月;
广西自然科学基金10万,2017年9月-2020年8月;
广西自然科学基金12万,2019年1月-2021年12月;
广西科技基地和人才专项12万,2019年6月-2022年5月;
桂林理工大学科研启动费10万,2016年12月—
电磁化学功能物质重点实验室基金3万,2018年1月-2019年12月;
五、主要研究论文
[1] Guangbin Jiang*, Guang Yang, Xinqiang Liu, Shoucai Wang, Fanghua Ji*. Palladium-catalyzed sequential acylation/annulation of indoles with acyl chlorides using primary amine as the directing group. New J. Chem., 2021, 45, 104-109. (SCI三区,IF:3.288)
[2] Xuan Li, Shoucai Wang, Jiawang Zang, Meichen Liu, Guangbin Jiang*, Fanghua Ji*. Copper- and DMF-mediated switchable oxidative C-H cyanation and formylation of imidazo[1,2-a]pyridines using ammonium iodide. Org. Biomol. Chem., 2020, 18, 9100-9108. (SCI二区,IF:3.412) (研究生第一作者).
[3] Yumei Zeng, Haiyang Zhang, Yujie Zhang, Fanghua Ji*, Jinlu Liang*, Shuhua Zhang*. Synthesis, crystal structures, fluorescence, electrochemiluminescent properties, and Hirshfeld surface analysis of four Cu/Mn Schiff-basecomplexes. Appl Organomet Chem. 2020;e5712.(SCI三区,IF:3.14) (研究生第一作者).
[4] Shoucai Wang, Siyu Zhang, Meichen Liu, Jiawang Zang, Guangbin Jiang*, Fanghua Ji*, Palladium-catalyzed C3-selective C-H oxidative carbonylation of imidazo[1,2-a]pyridines with CO and alcohols: a way to access esters. Org. Chem. Front. 2020, 7, 697-701.(SCI一区top,IF:5.076) (研究生第一作者).
[6] Shoucai Wang, Kai Wang, Xiangfei Kong, Shuhua Zhang, Guangbin Jiang*, Fanghua Ji*, DMF as Methine Source: Copper-Catalyzed Direct Annulation of Hydrazides to 1,3,4-Oxadiazoles. Adv. Synth. Catal. 2019, 361, 3986-3990. (SCI一区top,IF:5.123) (研究生第一作者).
[7] Guangbin Jiang*, Shoucai Wang, Jun Zhang, Jianwen Yu, Ziang Zhang, Fanghua Ji*, Palladium-catalyzed primary amine-directed decarboxylative a Annulation of α-oxocarboxylic acids : Access to indolo[1,2‑a]quinazolines. Adv. Synth. Catal. 2019, 361, 1798-1802. (SCI一区top,IF:5.123) (研究生第一作者).
[8] Fanghua Ji, Jianxiao Li, Xianwei Li, Wei Guo, Wanqing Wu, Huanfeng Jiang*, Carbonylation access to phthalimides using self-sufficient directing group and nucleophile. J. Org. Chem., 2018, 83, 104-112 (SCI二区top,IF:4.849).
[9] Fanghua Ji, Hui Peng, Xiaoting Zhang, Wenhua Lu, Shubin Liu, Huanfeng Jiang, Bo Liu*, Biaolin Yin*, Base-mediated decomposition of amide-substituted furfuryl tosylhydrazones: synthesis and cytotoxic activities of enynyl-ketoamides. J. Org. Chem., 2015, 80, 2092-2102 (SCI 二区top,IF:4.849).
[10] Fanghua Ji, Xianwei Li, Wei Guo, Wanqing Wu, Huanfeng Jiang*, Palladium-catalyzed oxidative O-H/N-H carbonylation of hydrazides: An access to substituted 1,3,4-oxadiazole-2(3H)-ones. J. Org. Chem., 2015, 80, 5713-5718 (SCI 二区top,IF:4.849).
[11] Fanghua Ji, Xianwei Li, Wanqing Wu, and Huanfeng Jiang*, Palladium-catalyzed oxidative carbonylation for the synthesis of polycyclic aromatic hydrocarbons (PAHs). J. Org. Chem., 2014, 79, 11246-11253 (SCI 二区top,IF:4.849).
[12] Wei Guo, Dongqing Liu, Jianhua Liao, Fanghua Ji, Wanqing Wu, and Huanfeng Jiang*, Cu-catalyzed intermolecular [3+3] annulation involving oxidative activation of an unreactive C(sp3)-H bond: access to pyrimidine derivatives from amidines and ketones. Org. Chem. Front., 2017, 4, 1107-1111 (SCI一区top, IF: 5.076).
[13] Wei Guo, Jianhua Liao, Dongqing Liu, Jiawei Li, Fanghua Ji, Wanqing Wu, and Huanfeng Jiang*. A four-component reaction strategy for pyrimidine carboxamide synthesis. Angew. Chem. Int. Ed., 2017, 56, 1289-1293 (SCI一区top, IF: 12.102).
[14] Wei Guo, Chunsheng Li, Jianhua Liao, Fanghua Ji, Dongqing Liu, Wanqing Wu, and Huanfeng Jiang*. Transition metal free intermolecular direct oxidative C-N bond formation to polysubstituted pyrimidines using molecular oxygen as the sole oxidant. J. Org. Chem., 2016, 81, 5538-5546 (SCI二区top, IF: 4.849).
[15] Wei Guo, Kunbo Huang, Fanghua Ji, Wanqing Wu, and Huanfeng Jiang*, A facile approach to synthesize 3,5-disubstituted-1,2,4-oxadiazoles via copper-catalyzed-cascade annulation of amidines and methylarenes. Chem. Commun., 2015, 51, 8857-8860 (SCI一区top, IF: 6.290).
[16] Xiaoyu Zhang, Li Huang, Hui Peng, Fanghua Ji, Xuehui Li, Biaolin Yin*. Access to fused pyrroles via the reaction of spiro-dienyl ethers with amines involving a chemoselective skeletal rearrangement. Tetrahedron. 2014, 70, 5242-5248 (SCI三区, IF: 2.377).
[17] Biaolin Yin, Li Huang, Xiaoyu Zhang, Fanghua Ji, Huanfeng Jiang. Cu(II)-promoted transformations of alpha-thienylcarbinols into spirothienooxindoles: Regioselective halogenation of dienyl sulfethers containing electron-rich aryl rings. J. Org. Chem., 2012, 77, 6365-6370 (SCI二区top, IF: 4.849).
[18] Biaolin Yin, Guohui Zeng, Congbi Cai, Fanghua Ji, Li Huang, Zhengrong Li, Huanfeng Jiang. Facile Synthesis of 3a,6a-dihydro-furo[2,3-b]furans and polysubstituted furans involving dearomatization of furan ring via electrocyclic ring-closure. Org. Lett., 2012, 14, 616-619 (SCI一区top, IF: 6.492).
六、授权专利
[1] 及方华. 一种利用羰基化反应一步构建靛红酸酐及其衍生物的合成方法,国家发明专利,ZL201710419937.6
[2] 及方华,王守才. 一种利用羰基化反应三步合成吴茱萸碱的方法. 国家发明专利,ZL201710893048.3
[3] 江焕峰,及方华,伍婉卿. 一种BMS-191011的合成方法. 国家发明专利,ZL201510103549.8
[4] 江焕峰,及方华,伍婉卿. 利用羰基化反应一锅法合成类TRPA1调节剂前体的方法. 国家发明专利,ZL2015102935732
[5] 江焕峰,及方华,伍婉卿. 一种利用羰基化反应一锅法合成N-取代的邻苯二甲酰亚胺的方法. 国家发明专利,ZL201510448013X
七、联系方式
通信地址:广西桂林市建干路 12 号,桂林理工大学化学与生物工程学院 (541004)
E-mail:fanghuaji@glut.edu.cn