李世清，男，汉族，1989年9月出生于湖南省邵阳市，理学博士，2017年6月进入桂林理工大学化学与生物工程学院，从事教学与科研工作。

一、教育背景： 

2008/9-2012/6 云南大学化学科学与工程学院，化学，本科（毕业论文导师：林军）

2012/9-2014/6 四川大学，化学学院，有机化学，硕士（导师：高戈/游劲松） 

2014/9-2017/6 四川大学，化学学院，有机化学，博士（导师：高戈/游劲松）

2017/6-2021/11 桂林理工大学，化学与生物工程学院，讲师

2022/9-2023/7 南开大学，化学学院，访问学者（合作导师：朱守非/赵东兵）

2021/11至今 桂林理工大学，化学与生物工程学院，副教授

二、主讲课程：

《有机化学》、《大学化学》、《普通化学》、《无机化学》

三、研究方向： 

有机合成方法学（新试剂与新反应）、C-H键功能化/串联反应与机制研究、高价碘化学、有机光电材料和药物分子的设计与合成。课题组主页：https://www.x-mol.com/groups/LI_Shiqing-GLUT

四、主持的科研项目：

（1）国家自然科学基金，地区基金项目，22261013，环状酸酐介导无痕策略促使无机肼转化成有机含氮氮双键化合物研究，2023.01-2026.12，33万。

（2）国家自然科学基金，青年基金项目，22001049，C-H活化/联导向基策略一步构筑（轴手性）联异喹啉衍生物及其金属螯合物的应用，2021.01-2023.12，24万。

（3）广西自然科学基金，青年基金项目，2020GXNSFBA297003，2021.01-2023.12，8万。

（4）广西自然科学基金联合资助培育项目，2018GXNSFAA294037，2019.01-2021.04，20万。

（5）广西科技基地和人才专项，AD19245095，2020.01-2022.12，10万。

五、代表性成果（论文）

2023

[24] Y. Yang, R. Xie, Y. Wang, P. Zhu, J. Wang, S. Li*. Efficient synthesis of benzo[c]cinnolines and azoarenes via dual C−N coupling of phthalhydrazide and trivalent halogen reagents. Org. Chem. Front. 2023, DOI: 10.1039/D3QO00391D. (SCI一区)

 

[23] C. Wen, Y. Wang, Y. Yang, Y.-N. Tian, J. Wang, S. Li*. Hydrazone-oxime Selectively Directed Redox-Neutral [4+2] Annulations Cascade with Alkynes and Iodonium Ylides to Build 1,1′-Biisoquinoline Mono‑N‑oxides. Org. Lett. 2023, 25, 2616–2621. (SCI一区)

[22] R. Xie,^‖ Y. Xiao,^‖ Y. Wang, Z.-W. Xu, N. Tian, S. Li*, M.-H. Zeng*. Hydrazine−Halogen Exchange Strategy Toward N=N-Containing Compounds and Process Tracking for Mechanistic Insight. Org. Lett. 2023, 14, 2415–2419. (^‖Equal contribution) (SCI一区，封面文章)

    

[21] Y. Wang, Y.-N. Tian, S. Ren, R. Zhu, B. Huang, Y. Wen, S. Li*. Metal-free homo-/cross-anion–cation coupling of cyclic diaryl λ³-bromanes. Org. Chem. Front. 2023, 10, 793–798. (SCI一区)

[20] Y.-N. Tian, S. Lv, L. Huang, C. Wen, Y. Yang, X. Kong, Q. Zhu*, S. Li*. Experimental and computational studies on rhodium-catalyzed C4(5)_aryl−H activation/annulations of imidazoles with alkynes: facile synthesis of six types of N-heterocycles. Org. Chem. Front. 2023, 10, 83−91. (SCI一区)

 

2022

 

[19] L. Huang, Y.-N. Tian, S. Ren, J. Wang, Y. Xiao, Q. Zhu*, S. Li*. Palladium-catalysed dual ring-opening [3 + 4] annulation of isatoic anhydrides with cyclic iodoniums to build tribenzo[b,d,f]azepines and a mechanistic DFT study. Org. Chem. Front. 2022, 9, 6259-6264. (SCI一区)

 

[18] S. Lv, Y.-N. Tian, Y. Yang, C. Wen, S. Li*. Rh(III)-Catalyzed One-Pot Three-Component Diannulation of Benzils, Ammonium Acetate, and Alkynes to Build 1,1′-Biisoquinolines. J. Org. Chem. 2022, 87, 16019−16025. (SCI二区)

 

[17] L. Huang‡, R. Xie‡, C. Wen, Y. Yang, Y. Wang, S. Ren, B. Huang, S. Li*. Decarbonylative /decarboxylative [4 + 2] annulation of phthalic anhydrides and cyclic iodoniums towards triphenylenes. Org. Biomol. Chem. 2022, 20, 3913–3916. (‡ Equal contribution, Highlighted by Synfacts) (SCI三区)

[16] Y. Wang‡, Y. Yu‡(本科生), R. Xie, Y.-N. Tian, L. Huang, S. Lv, X. Meng, X. Kong, S. Li*. Cu/Fe-mediated N(sp²)-arylation/alkenylation of pyridines with aryl-/alkenylboronic acids to yield versatile cationic materials. New J. Chem. 2022, 46, 2320–2325. (‡ Equal contribution) (SCI三区)

2021

[15] Y. Wang (推免至华中师范大学读博), R. Xie, L. Huang, Y.-N. Tian, S. Lv, X. Kong, S. Li*. Divergent synthesis of unsymmetrical azobenzenes via Cu-catalyzed C–N coupling. Org. Chem. Front. 2021, 8, 5962–5967. (SCI一区)

 

[14] X. Kong, R. Luo, H. Gong, D. Chen, S. Yang, S. Li*, G. Wang*, Z. He*. Discotic liquid crystals with aggregation-induced emission properties based on tetraphenylethylene and triphenylene derivatives. Mol. Cryst. Liq. Cryst. 2021, 724, 26−37.

2020

[13] S. Li*, H. Lv, R. Xie, X. Ye, X. Kong*. The C−H Activation/Bidirecting Group Strategy for Selective Direct Synthesis of Diverse 1,1′-Biisoquinolines. Org. Lett. 2020, 22, 4207−4212. (SCI一区)

 

[12] R. Xie,^# H. Lv,^# X. Ye, X. Kong*, S. Li*. Cu-Catalyzed tandem N-arylation of phthalhydrazides with cyclic iodoniums to yield dihydrobenzo[c]cinnolines. Org. Biomol. Chem. 2020, 18, 4824−4830. (^# Equal contribution) (SCI三区)

[11] Y. Yu (本科生), H. Lv, S. Li*. The C–H functionalization of organic cations: an interesting and fresh journey. Org. Biomol. Chem. 2020, 18, 8810–8826. (SCI 三区)

2019 

[10] S. Li*, H. Lv (推免至华东师范大学读博), Y. Yu, X. Ye, B. Li, S. Yang, Y. Mo, X. Kong*. Domino N-/C- or N-/N-/C-arylation of imidazoles to yield polyaryl imidazolium salts via atom-economical use of diaryliodonium salts. Chem. Commun. 2019, 55, 11267−11270. (SCI一区)

 

2018以前

[9] S. Li, J. Tang, Y. Zhao, R. Jiang, T. Wang, G. Gao*, J. You*, Cu-Catalyzed Controllable C−H Mono-/Di-/Triarylations of Imidazolium Salts for Ionic Functional Materials, Chem. Commun. 2017, 53, 3489−3492.

[8] S. Li, F. Yang, T. Lv, J. Lan, Ge Gao*, J, You*, Synthesis of unsymmetrical imidazolium salts by direct quaternization of N-substituted imidazoles using arylboronic acids, Chem. Commun. 2014, 50, 3941−3943.

[7] Y. Zhao, S. Li, X. Zheng, J. Tang, Z. She, G. Gao*, J. You*, Rh/Cu-Catalyzed Cascade [4+2] Vinylic C−H O-Annulation and Ring Contraction of a-Aryl Enones with Alkynes in Air, Angew. Chem. Int. Ed. 2017, 56, 4286−4289. （国际顶级期刊）

[6] J. Tang, S. Li, Z. Liu, Y. Zhao, Z. She, V.s D. Kadam, G. Gao*, J. Lan, J. You*，Cascade C−H Annulation of Aldoximes with Alkynes Using O2 as the Sole Oxidant: One-Pot Access to Multisubstituted Protoberberine Skeletons, Org. Lett. 2017, 19, 604-607.

[5] X. Li, S. Li, G. Gao, D. Wu, J. Lan*, R. Wang*, J. You*，High Performance Ruthenium Sensitizers Containing Imidazoliums as Counterions for the Efficient Dye-Sensitization in Water, ChemSusChem. 2017, 10, 2914−29121. 

[4] H. Zhou, Y., Zhao, G. Gao*, S. Li, J. Lan, J. You*, Highly Selective Fluorescent Recognition of Sulfate in Water by Two Rigid Tetrakisimidazolium Macrocycles with Peripheral Chains, J. Am. Chem. Soc. 2013, 135, 14908−14911. （国际顶级期刊）

[3] Z. He, X. Qi, S. Li, Y. Zhao, G. Gao*, Y. Lan*, Y. Wu, J. Lan, J. You*, Transition-Metal-Free Formal Decarboxylative Coupling of α-Oxocarboxylates with α-Bromoketones under Neutral Conditions: A Simple Access to 1,3-Diketones, Angew. Chem. Int. Ed. 2015, 54, 855−859.（国际顶级期刊）

[2] Y. Zhao, Z. He, S. Li, J. Tang, G. Gao*, J. Lan, J. You*, An Air-stable Half-sandwich Ru^II complex as an efficient Catalyst for [3+2] Annulation of 2-Arylcyclo-2-enones with Alkynes, Chem. Commun. 2016, 52, 4613−4616.

[1] Z. He, X. Qi, Z. She, Y. Zhao, S. Li, J. Tang, G. Gao*, Y. Lan*, J. You*, Room-Temperature Coupling/Decarboxylation Reaction of α‑Oxocarboxylates with α‑Bromoketones: Solvent-Controlled Regioselectivity for 1,2- and 1,3-Diketones, J. Org. Chem. 2017, 82, 1403−1411.

六、授权发明专利

[1] 李世清，李永树，梁霞静，刘运烽，陈紫园，潘梅玲. 联苯基桥联双苯并咪唑鎓的制备方法及其应用，中国发明专利，ZL 201811538437.5，2022年3月22日授权。

[2] 李世清，吕洪旭，余雨，叶秀青，黎柏松，杨松明，莫炎儒. 一种由二芳基碘鎓盐与咪唑合成五芳基咪唑鎓盐的方法，中国发明专利，ZL 201910658316.2，2022年8月9日授权。

七、招生与联系方式

招生：招收化学、化学工程与技术、材料与化工等专业一志愿以及调剂录取的硕士研究生，欢迎有机化学爱好者报考本课题组！也欢迎喜欢科研的本科生加入课题组！

地址：桂林理工大学雁山校区9栋504室，邮箱（优先）：LSQ030080@126.com，电话：19907736780