一、基本情况
肖文成，男，汉族，1993年7月生，湖南邵阳人；博士。主要从事均相化学发光免疫分析、生物传感器、微流控技术。
二、学习与工作经历
2011.9-2015.6 吉首大学，化学化工学院，食品质量与安全，工学学士
2016.9-2019.6 桂林理工大学，化学与生物工程学院，化学工程与技术，工学硕士
2020.9-2026.6 南京大学，化学学院，化学，理学博士
2026.7-至今 桂林理工大学，讲师
三、所获奖项及相关社会任职
无
四、教学工作
无
五、科研项目
1.国家自然科学基金国家重大科研仪器研制项目，21827812，特异性抗体可视化筛选的微流控装置，2019/01-2023/12，780万元，主要参与人
六、近年发表论文/授权专利
1. Wencheng Xiao, Yaqi Bai, Hang Ao, Xing Liu, Jie Wu,* Jun Sun, Nilin Wu, Wenrui Hu, Yunlong Chen, Yanjian Liao, Ning Hu,* and Huangxian Ju*. A fully integrated microfluidic device for cell electrofusion and quick acquisition of hybridoma cells with high production of monoclonal antibody. Biosens. Bioelectron. 2026, 304, 118614.
2. Wencheng Xiao, Hang Ao, Nilin Wu, Jun Sun, Wenrui Hu, Yunlong Chen, Jie Wu,* and Huangxian Ju*. Hemin-DNA switch-assisted microfluidic chemiluminescence immunoimaging for rapid and quantitative screening of specific hybridomas. Anal. Chem. 2026, 98, 2541–2549.
3. Wencheng Xiao, Yiming Gao, Yun Zhang*, Jiao Li, Zhaoying Liu, Jinfang Nie*, and Jianping Li. Enhanced 3D paper-based devices with a personal glucose meter for highly sensitive and portable biosensing of silver ion. Biosens. Bioelectron. 2019, 137, 154−160.
4. Wencheng Xiao, Zihao Deng, Jinkun Huang, Ziheng Huang, Miaomiao Zhuang, Yali Yuan, Jinfang Nie*, and Yun Zhang*. Highly sensitive colorimetric detection of a variety of analytes via the Tyndall effect. Anal. Chem. 2019, 91, 15114−15122.
5. Hang Ao1, Wencheng Xiao1, Weiwei Chen, Wenrui Hu, Jie Wu,* and Huangxian Ju*. A microcavity chemiluminescent immunoimaging protocol for fast in situ detection of antibody secreted from single hybridoma cells. Small Methods 2025, 2500656.
6. Hang Ao1, Wencheng Xiao1, Wenrui Hu, Jie Wu,* and Huangxian Ju*. DNA conformation-regulated hemin switch for lab-on-chip chemiluminescent detection of an antibody secreted from hybridoma cells. Anal. Chem. 2024, 96, 18502−18509.
7. Hang Ao, Wencheng Xiao, Yuhui Chen, Jie Wu*, Huangxian Ju*. Target-triggered parallel rolling circle amplification circuits for chemiluminescent imaging assay of proteins. Sens. Actuator B-Chem. 2023, 383, 133579.
8. Shuai Luo, Weiwei Chen, Yuru Wang, Wenrui Hu, Wencheng Xiao, Jie Wu, and Huangxian Ju*. Transforming chemiluminescence from flash to glow by breaking the catalytic limitation with a medium-entropy nanozyme. Angew. Chem. Int. Ed. 2025, e202503734.
9. Jun Sun, Ran Chu, Xiaoqian Wu, Qian Yu, Wencheng Xiao, Hang Ao, Yuru Wang, Taikang Wu, Huangxian Ju, Jie Wu,* and Jianping Lei*. Anti-biopassivated reticular micromotors for bladder cancer therapy. J. Am. Chem. Soc. 2025, 147, 17936−17945.
10. Hang Ao, Jinshan Xiong, Wencheng Xiao, Wenrui Hu, Jie Wu*, Huangxian Ju*. Imidazole-enhanced luminol/H2O2 chemiluminescent system for SARS-CoV-2 nucleocapsid protein detection via enzymatic regulation of hemin switch. Biosens. Bioelectron. 2025, 118002.
11. Qian Yu, Jie Wu, Wencheng Xiao, Chao Zhao, Weiqi Zhang, Yunlong Chen, Ying Liu, Hong Liu, Jun Zhou, Lin Ding, and Huangxian Ju*. An integrated, wearable paper microfluidic array device for multicomponent electrochemical sweat sensing. Cell Rep. Phys. Sci. 2025, 6, 102389.
12. Hang Ao, Weiwei Chen, Jie Wu✉, Wencheng Xiao & Huangxian Ju✉. Chemiluminescent screening of specific hybridoma cells via a proximity-rolling circle activated enzymatic switch. Commun. Biol. 2022, 5, 308.
13. Ningning Wang, Hang Ao, Wencheng Xiao, Weiwei Chen, Guangming Li, Jie Wu, Huangxian Ju*. Confined electrochemiluminescence imaging microarray for high-throughput biosensing of single cell-released dopamine. Biosens. Bioelectron. 2022, 201, 113959.
14. 鞠熀先, 吴洁, 肖文成, 一种用于细胞融合、单细胞筛选和单克隆抗体生产的设备，2025.09.05，中国，202511261191.1。
15. 鞠熀先, 吴洁, 肖文成, 单克隆抗体的化学发光均相检测方法和试剂盒，2025.09.05，中国，202511261174.8。
16. 鞠熀先, 吴洁, 肖文成, 一种单细胞分泌物化学发光成像检测用微流控芯片及其使用方法，2025.09.05，中国，202511261211.5。
17. 鞠熀先, 吴洁, 肖文成, 一种用于特异性单细胞筛选的微流控芯片及其使用方法，2025.09.05，中国，202511261145.1。
18. 吴洁, 鞠熀先, 肖文成, 胡文瑞，一种化学发光数字免疫检测方法和试剂盒，2025.05.29，中国，202510652879.6。
七、联系方式：
通信地址：广西桂林市建干路12号，桂林理工大学化学与生物工程学院(541004)
E-mail：wcxiao@glut.edu.cn
